How Long Will It Take to Get the Results (Interpretation) of Your Liver Blood Tests? An infection or a reaction to medication might affect your blood test results and sometimes a repeat liver blood test is all that’s needed. Mild elevations are generally considered to be 2-3 times higher than the normal range. Common causes of elevated ALT and AST are viral liver infections, alcohol abuse, cirrhosis (from any chronic causes), and more. If your results are abnormal your GP can advise you on the next steps to determine the cause and assess how serious the problem and any associated damage is. 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These may include malaise, fatigue, fever, poor appetite, abdominal pain, jaundice (yellowing of skin), itching, nausea, or vomiting. The Government advises that both men and women should not regularly drink more than 14 units in a week. See Additional Information. Liver blood tests look at how well the liver is functioning and can indicate whether there is any damage or inflammation inside the liver. LD. The most common diseases causing abnormally elevated ALT and AST are acute viral hepatitis, such as. Some common ones include: Alanine transaminase (ALT) test. Some of these conditions include: The most important step in evaluating patients with abnormal liver enzyme levels is to take a thorough medical history and perform a complete medical examination. There also are other liver enzymes such as, lactate dehydrogenase (LDH), glutamate dehydrogenase, and gamma-glutamyltranspeptidase (GGT), which are less routinely measured clinically. Common causes for this are gallbladder obstruction and certain medications. If you have NAFLD, the next step is to investigate the extent of the condition and if the liver is scarred or damaged. A liver blood test looks at the chemicals (enzymes), proteins and other substances made by the liver to assess whether levels of any of these are abnormal. This requires a second panel (set) of blood tests that look for potential causes such as viruses, problems with the immune system and rarer inherited conditions. home They can also be severely elevated, possibly up to 10 to 20 times the normal values, suggesting more significant damage to the liver. Albumin levels may decrease if the liver is damaged. Alanine transaminase (ALT) is used by your body to metabolize protein. An increase of bilirubin causes jaundice, characterised by a yellowing of the eyes and skin in liver disease. AST. Intentional medication overdose, such as acetaminophen (Tylenol liver damage). Liver tests are common blood tests used to determine if the liver is functioning normally. These are enzymes found mainly in the bile ducts of the liver. REFERENCE: Diagnosing Liver Disease - Liver Biopsy and Liver Function Tests. Some anti-fungal medications, for example. Monitoring levels of these enzymes can help doctors assess how much liver scarring (fibrosis) there is in conditions such as non-alcohol related fatty liver disease (NAFLD) and alcohol-related liver disease. If they are abnormal, your doctor will also explain the most likely cause, and how severely affected your liver may be. However, any abnormality does need to be investigated to find out what the cause is. Hepatitis C virus causes an infection of the ______________. If your GP thinks it’s appropriate, they will perform a panel of routine liver blood tests and relevant care or treatment can be discussed from there. If these tests are not able to assess any damage accurately, a liver biopsy may be considered to provide more detailed information. In some conditions, these enzymes can be severely elevated, in the 1000s range. Many drugs may cause elevated blood levels of AST, and ALT and some medications can cause severe damage, for example, acetaminophen (Tylenol). People with mild to moderate elevations of AST and ALT may have no symptoms or mild systemic symptoms. Abnormal liver blood test results are relatively common and most people with these results have normal liver function. Please download the Liver Disease Tests Explained publication for further information. In many instances, a doctor may also order an ultrasound of the liver to assess the structure of the liver and the biliary tree as well to look for any gallstones that may be causing the liver disease. 40 to 129 U/L 4. American Liver Foundation. The levels of each of these will be given in numbers and values. 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