T2DM and age 40-75 years, use moderate-intensity statin and risk estimate to consider high-intensity statins. There are several different types of statins. It was the statin used in the 20,000-patient Heart Protection Study, showing a reduced risk of heart attack at all LDL cholesterol … Drug Comparisons Statins (HMG-CoA Reductase Inhibitors) ' -- ' Signifies that equivalent tablet size is not available (comparable dose is either too high or too low) Drug Comparisons - Home … Simplified flow chart of major considerations for statin selection or substitution. intensity statin if: LDL > 160 mg/dl, family history, hs CRP > 2, CAC>300 or 75%, ABI < .9, or high lifetime risk. … Statin Treatment Recommendations. Some are more potent than others. However, expert recommendations lean toward a moderate-intensity or high-intensity statin. Statin Selection or Substitution. FIGURE. Manufacturer: Merck Pros: potent at raising HDL cholesterol. The following are guideline recommendations for statin treatment: Patients ages 20-75 years and LDL-C ≥190 mg/dl, use high-intensity statin without risk assessment. Statins 101. Clinical atherosclerotic cardiovascular disease LDL-C ≥ 190 mg/dl Type 1 or 2 Diabetes age 40-75 Age 40-75 Estimated 10 yr atherosclerotic CVD risk > 7.5% High-Intensity Statin …